July 30, 2025 USTFA

Ovaprim has Now been Indexed for Use in All Finfish Broodstock

Courtesy of NAA:

Ovaprim is a potent ovulating/spermiating agent used to promote and facilitate reproduction of many species of fish. Ovaprim is a stable solution that contains OvaRH and a dopamine inhibitor. Ovaprim utilizes the fish’s own endocrine system to safely induce maturation and coordinate spawning dates. When used in the normal spawning cycle, Ovaprim can synchronize and coordinate maturation in treated fish by inducing maturation without affecting viability or fecundity, resulting in highly predictable ovulation, with high egg fertility and viability.

The Index of Legally Marketed Unapproved New Animal Drugs for Minor Species is a means, authorized by the Minor Use, Minor Species Animal Health Act, to approve the use of Ovaprim by the Food and Drug Administration, Center for Veterinary Medicine (FDA CVM), on broodstock as long as the fish will never be harvested for human consumption. This alterative pathway to legal use offers a less burdensome and less expensive option for drug sponsors to bring therapeutants to market and expand the medicine chest for a variety of non-food aquaculture applications.

The label expansion was facilitated by an Expert Panel Report authored by Dr. Roy Yanong (University of Florida), Dr. Matt DiMaggio (University of Florida), and Dr. Shane Ramee (Aquatic Animal Drug Approval Partnership). This is the first indexed spawning hormone available for use in all finfish broodstock but hopefully it won’t be the last.

For information to select and use FDA CVM approved aquaculture medications, please click here.

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